Uterine Fibroids-Does Natural Progesterone Help?
Is this a case of Estrogen Dominence.
A pharmaceutical company that is developing drug that attaches to progesterone receptors to try to shrink fibroids; a (SPRM) selective progesterone receptor modulator. This selective progesterone receptor modulator (SPRM), which acts directly on the progesterone receptors in three target tissues: the endometrium (uterine lining), uterine fibroids, and the pituitary gland.
I would like to share my thought process that will reveal my hypothesis and get your opinions.
I will use the risk factors and prevalence of uterine fibroids stated by the drug rep as of 2016 to make my point.
(BTW, this is the opinion of other practitioners and these observations are from my clinical practice as well.)
If a women’s BMI>30 3x risk of uterine fibroids.
Which hormone is usually high is over weight women? ESTROGEN
The prevalence increases in 40s and...